hrp0094fc7.6 | Fetal Endocrinology and Multisystem Disorders | ESPE2021

Reassessment of 18F-DOPA PET cut-offs in congenital hyperinsulinism

Gubaeva Diliara , Ryzhkova Daria , Nikitina Irina , Mitrofanova Lubov , Tiulpakov Anatoly , Melikyan Maria ,

Introduction: Congenital hyperinsulinism (CHI) is a rare but severe condition causing persistent hypoglycaemia. Approximately 30-40% of patients require surgical treatment. Extent of surgery depends on the histological form of the disease: subtotal pancreatectomy is done in diffuse CHI, whereas pancreatic resection is recommended in focal CHI.18F-DOPA PET scan is a gold-standard imaging technique that helps in differential diagnosis of diffuse and f...